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マウス実験の基礎知識
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マウス実験の基礎知識

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「マウス実験の基礎知識」第2版

小出 剛



#小出剛 #小出_剛 #本 #自然/生物学



マウス実験の疑問を解決! ─実験計画から表現型解析,トランスジェニックマウスの作製方法まで,懇切丁寧に解説─

はじめてマウス実験を行う際におさえておきたい事柄をまとめた入門書です。マウスは,その遺伝子のうち99%がヒトの遺伝子と対応していて,かつ,遺伝子改変体の作製が可能な動物です。そのためマウスは,ヒトの疾患研究や創薬をはじめさまざまな研究分野で利用されています。

本書は,マウスの飼い方,体の構造,生活環,発生ステージ,系統,遺伝学,利用できるインターネット情報など,実験を行う前に得ておくべきマウスについての基礎知識を網羅しています。さらに,解剖,診断,脳組織の採取,行動解析,ノックアウトマウスの作製,などの実験手法についてもやさしく解説しています。

第2版では,上記に加え要望の多かった「マウスの体外受精法」「トランスジェニックマウスの作製法」など最新の話題を収録。



★このような方におすすめ

薬学部,理学部,農学部の大学生,大学院生,医学系の大学院生,バイオ系専門学校生,研究者



★主な内容

第1章 マウスを使って実験を始めよう

第2章 系統について知ろう

第3章 マウスの記録をつけてみよう

第4章 マウスの生活環について知ろう

第5章 マウスの解剖について知ろう

第6章 マウスの胎仔を見てみよう

第7章 マウスの体外受精はどうするの

第8章 マウスの脳を見てみよう

第9章 マウスを診断してみよう

第10章 マウスの行動を解析しよう

第11章 マウスのゲノムについて知ろう

第12章 マウスの遺伝学にチャレンジ

第13章 トランスジェニックマウスを作製しよう

第14章 ノックアウトマウスを作製しよう

第15章 コンピュータでマウスを研究しよう
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